Central European Journal of Sport Sciences and Medicine


ISSN: 2300-9705     eISSN: 2353-2807    OAI
CC BY-SA   Open Access   DOAJ  DOAJ

Lista wydań / Vol. 8, No. 4/2014
Exercise Induced Muscle Damage May Be Improved by a Single Dose of Intra-Muscular Platlet Rich Plasma- A Pilot Study

Autorzy: Ramazan Aydinoglu
School of Physical Education and Sport, University of Ege, İzmir, Turkey

Onur Orak
School of Physical Education and Sport, University of Ege, İzmir, Turkey

Nadir Ozkayin
Department of Orthopaedics and Traumatology Medical Faculty, University of Ege, Izmir, Turkey

Zekine Punduk
School of Physical Education and Sport, University of Balikesir, Balikesir, Turkey
Słowa kluczowe: Platlet rich plasma exercise induced muscle damage muscle recovery muscle soreness
Data publikacji całości:2014
Liczba stron:8 (19-26)

Abstrakt

Platelet-rich plasma (PRP) is being increasingly used in the modern medicine as a material stimulating, regenerating and accelerating tissue healing, including muscle injuries in sports. The aim of the present study was to determine the effect of PRP on strength recovery in exercise induced muscle damage (EIMD). A baseline value was established in six healthy male volunteers during maximal voluntary strength isometric contractions (MVC) of the elbow flexors in both arms. This was followed by MVC performance (80% IRM) concentric-eccentric exercise of both elbow flexors until point of exhaustion, and 24 h later the subjects were injected with PRP in the non-dominant arm (PRP-arm). Maximal isometric strength and muscle soreness was compared before and at 24, 48, 72 and 96 h after delayed onset muscle soreness (DOMS) between the arms. The results indicate that the muscle soreness was significantly decreased in PRP administered arm when compared to control-arm, however, the levels for isometric flexors peak torque (PT) and average strength (AS) significantly declined in the bout arm post exercise induced muscle damage. Administration of PRP had no effect on the muscle strength parameters, however, flexor PT values were higher in PRP administered arm compared to the control arm, but this was only achieved on the second day of post-exercise induced muscle damage.
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Bibliografia

1.Almekinders L.C. Anti-inflammatory treatment of muscular injuries in sport. An update of recent studies. Sports Med. 1999; 28 (6): 383–388.
2.Banfi G., Corsi M.M., Volpi P. Could platelet rich plasma have effects on systemic circulating growth factors and cytokine release in orthopaedic applications? Br J Sports Med. 2006; 40 (10): 816.
3.Bourgeois J., MacDougall D., MacDonald J.A.Y., Tarnopolsky M. Naproxen does not alter indices of muscle damage in resistanceexercise trained men. Med Sci Sports Exerc. 1999; 31 (1): 4–9.
4.Bubnov R., Viacheslav Y., Semeniv I. Ultrasound guided injections of Platelets Rich Plasma for muscle injury in professional athletes. Comparative study. Med Ultrason. 2013;.15.(2):.101–105.
5.Cheung K.H., Patria A., Maxwell L. Delayed onset muscle soreness: treatment strategies and performance factors. Sports Med. 2003; 33 (2): 145–164.
6.Clarkson P.M., Sayers S.P. Etiology of exercise-induced Muscle damage. Can J Appl Physiol. 1999; 24: 234–248.
7.Cleak M., Eston R. Muscle soreness, swelling, stiffness and strength loss after intense eccentric exercise. Br J Sports Med. 1992; 26: 267–272
8.Engebretsen L., Steffen K., Alsousou J., Anitua E., Bachl N., Devilee R., Everts P., Hamilton B., Huard J., Jenoure P., Kelberine F., Kon E., Maffuli N., Matheson G., Mei-Dan O., Menetrey J., Philippon M., Randelli P., Schamasch P., Schwellnus M., Vernec
9.Gobbi A., Bathan L. Biological approches for cartilage repair. J Knee Surg. 2009; 22 (1): 36–44.
10.Gosens T. Peerbooms J.C., van Laar W., den Oudsten B.L. Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a double-blind randomized controlled trial with 2-year follow-up. Am J Sports Med. 2011; 39 (
11.Hamid M.S.A., Ali M.R.M., Yusof A., George A. Platelet-rich plasma (PRP): an adjuvant to hasten hamstring muscle recovery. A randomized controlled trial protocol (ISCRTN66528592). BMC Musculoskelet Disord. 2012; 13: 2–8.
12.Hechtman K.S., Uribe J.W., Botto-vanDemden A., Kiebzak G.M. Platelet-rich plasma injection reduces pain in patients with recalcitrant epicondylitis. Orthopedics. 2011; 34: 92.
13.Jakeman J.R., Byrne C., Eston R.G. Lower limb compression garment improves recovery from exercise-induced muscle damage in young, active females. Eur J Appl Physiol. 2010; 109 (6): 1137–1144.
14.Kuipers H., Keizer H.A., Verstappen F.T., Costill D.L. Influence of a prostaglandin-inhibiting drug on muscle soreness after eccentric work. Int J Sports Med. 1985; 6 (6): 336–339.
15.Kuipers H. Exercise-induced muscle damage. Int J of Sports Med. 1994; 15: 132–135.
16.Lopez-Vidriero E., Goulding K.A., Simon D.A., Sanchez M., Johnson D.H. The use of platelet-rich plasma in arthroscopy and sports medicine: optimizing the healing environment. Arthroscopy. 2010; 26 (2): 269–278.
17.Malm C. Exercise-induced muscle damage and inflammation: Fact or fiction? Acta Physiol Scand. 2001; 171: 233–239.
18.Paulsen G., Egner I.M., Drange M., Langberg H., Benestad H.B., Fjeld J.G., Hallen J., Raastad T. A COX-2 inhibitor reduces muscle soreness, but does not influence recovery and adaptation after eccentric exercise. Scand J Med Sci Sports. 2010; 20 (1): 195–
19.Peerbooms J.C., Sluimer J., Bruijn D.J., Gosens T. Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1year follow-up. A
20.Semark A., Noakes T.D., Gibson A.S.C., Lambert M.I. The effect of a prophylactic dose of flurbiprofen on muscle soreness and sprinting performance in trained subjects. J Sports Sci. 1999; 17 (3): 197–203.
21.Tee J.C., Bosch A.N., Lambert M.I. Metabolic consequences of exercise-induced muscle damage. Sports Med. 2007; 37: 827–836.
22.Thanasas C., Papadimitriou G., Charalambidis C., Paraskevopoulos I., Papanikolaou A. Platelet-rich plasma versus autologous whole blood for the treatment of chronic lateral elbow epicondylitis: a randomized controlled clinical trial. Am J Sports Med. 2011
23.Virchenko O., Aspenberg P. How can one platelet injection after tendon injury lead to a stronger tendon after 4 weeks? Interplay between early regeneration and mechanical stimulation. Acta Orthop. 2006; 77 (5): 806–812.
24.Wasterlain A.S., Braun H.J., Harris A.H., Kim H.J., Dragoo J.L. The systemic effects of platelet-rich plasma injection. Am J Sports Med. 2013; 41 (1): 186–193.
25.Zhang J., Clement D., Taunton J. The efficacy of Farabloc, an electromagnetic shield, inattenuating delayed-onset muscle soreness. Clin J Sport Med. 2000; 10 (1): 15–21.